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Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15

[11] There is a widening of the muscular hiatal tunnel and circumferential laxity of the phrenoesophageal ligament, allowing a portion of the gastric cardia to herniate upward into the posterior mediastinum

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45,57,317,318 Three neuromodulation deviceselectrical trigeminal nerve stimulation, noninvasive vagus nerve stimulation, and single-pulse transcranial magnetic stimulation ( TABLE 3 )are FDA approved for migraine prevention as monotherapy or used adjunctively, as described in the Abortive Treatment section

"Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats"