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Note, a reduction in bodyweight, RV hypertrophy, and an increase in RV weight still occur when treatment involves a endothelin receptor antagonist (e.g., macitentan) [22,23,78], and thereby, the underlying pathogenesis of the monocrotaline model continues to progress, and pulmonary hypertension continues to develop despite the treatment [21], unlike the noted elimination in the BPC 157 regimens

Individual variation is also real

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This makes sense given BPC-157's effect on angiogenesis and blood flow restoration

When administered together, BPC-157 and TB-500 produce 40-60% greater improvements in healing outcomes compared to either peptide alone, as measured by tensile strength recovery in tendon models, wound closure rates in dermal models, and inflammatory marker reduction in systemic inflammation models