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Journal of Drug Vigilance and Alternative Therapies

Lawrence, R.A

32 GST in regulation of MAPK pathway Besides metabolite detoxification, GST also exhibits ligand-binding properties that allow the enzyme to interact covalently and noncovalently with compounds, resulting in inhibition of conjugation activity

Whilst we found that melatonin did not affect the concentration of G6P ( Figure 5H ), it did seem to greatly reduce the amount of F6P present in our cell samples, indicating potentially that the key disruption to this pathway occurred at the step where G6P is converted to F6P ( Figure 5E )

Tran KT, Lamb P, Deng J-S (2005) Matrikines and matricryptins: implications for cutaneous cancers and skin repair

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