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We thank Catherine Sampson for her assistance with the mouse blood collection and epididymis fat-pad isolation procedures

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29, 30 This layering of antioxidants provides broad spectrum coverage across multiple oxidative pathways, providing greater protection

Taken together, the present findings suggest CD38 as an immunometabolic checkpoint that could be adopted as a pre-symptomatic biomarker for early diagnosis of AD, and might also be therapeutically targeted alone or in combination with other immunotherapies for disease modification

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