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SLC7A11 expression is enhanced by TMZ via Nrf2 and ATF4 activation pathway, and erastin-inhibited SLC7A11 enhances TMZ toxicity (173)

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NOX inhibition targets NADPH oxidases at the plasma membrane and within organelles: using selective NOX1/4 blockers or broader pan-NOX agents can dampen site-specific ROS generation, which in turn may slow fibrotic remodeling, protect endothelial function and vascular tone, and ease downstream metabolic stress

Of course, like any dried fruit, eating too much can be borderline unhealthy because of their high sugar content and calories

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