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Microbiota-derived short-chain fatty acids: Implications for cardiovascular and metabolic disease

18: 1-7 Gkountela S, Zhang KX, Shafiq T, Liao W-W, Hargan-Calvopina J, P-Y Chen, Clark, AT (2015)

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Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin

In addition, the sensitivity of iMAT approach to user defined threshold typically leads to higher number of reactions to be omitted or sometimes leads to exclusion of important reactions from the pruned model