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In natural killer T-cell lymphoma (NKTCL), blocking SLC1A1-mediated glutamine addiction in tumor cells induced PD-L1 expression and inhibited CD8(+) T-cell activity 149

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This dynamic process plays an essential role in cellular adaptation to stress, including nutrient deprivation, hypoxia, and metabolic imbalance

Furthermore, therapeutic strategies using glucagon receptor antagonists to reduce high blood glucose in diabetics need to be reassessed, as they may negatively impact the function of the cells that produce insulin, the hormone diabetic patients need the most. Although their translational research involved both human tissue and mice, the researchers emphasized one uniquely human point

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