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Many studies have shown that polyphenolic compounds, mainly found in tea, coffee, cocoa, and some fruits and vegetables, inhibit iron absorption [222, 223, 272]

Thus, the clinical and experimental studies convincingly show the involvement of mitochondrial abnormalities in RS, although the mechanisms underlying the role of mitochondrial dysfunction need further investigation

The most commonly employed methods for the synthesis of SiNPs are the Stober's process and the microemulsion method (Figure 1)

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