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The authors also noted that further optimisation was needed, including work relating to high clearance in mice and off-target activity against monoamine oxidase A

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Moreover, no inactivating mutation of GSTM2 has been found in human or house mouse

Its use can be traced back several centuries as a natural remedy for everything from bronchitis to diarrhea

Gao Z, Wang G, Chen Y et al (2024) Total flavonoids of Astragalus membranaceus protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice by inhibiting ferroptosis through SLC7A11/GPX-4 signaling pathway

doi:10.7150/ijbs.77141 This issue Cite Review 1