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Brazilian Archives Biology Technol

150,151 Cadmium changes the redox status of cells by reducing glutathione levels and increasing reactive oxygen and nitrogen species, resulting in the inhibition of OGG1

doi: 10.3390/ph18060928

Nebe, V

In contrast to trabectedin, that exhibited dose-dependent cytotoxicity, BBGC treatment at increasing doses (up to the limits of solubility) did not affect cell viability in any of the cell lines, as the half-maximal inhibitory concentration (IC50) was not reached (Fig