Androgenic alopecia: cross-talk between cell signal transduction pathways
The following antibodies were used: cytokeratin 7 (CK7/KRT7) (Abcam, ab181598, 1:1000), CYP3A4 (Invitrogen Antibodies, MA5-17064, 1:1000), desmin (R&D Systems, AF3844, 1:20), and albumin (Fortis Life Sciences, A80-129 A, 1:1000)
10.1002/biof.1544 21 ChekhunV
Association between preoperative de ritis (Ast/Alt) ratio and oncological outcomes following radical cystectomy in patients with urothelial bladder cancer
Abstract 5-Fluorouracil (5-FU) resistance in colorectal cancer (CRC) involves oxidative stress mechanisms, but the role of epitranscriptomic regulation remains unclear
The equilibrium established between pro-apoptotic proteins, exemplified by Bax, and anti-apoptotic counterparts such as Bcl-2, critically influences cellular fate in response to stressors ( The signaling pathways of TGF- have been demonstrated to exert significant influence over apoptotic mechanisms, either facilitating or restraining apoptosis contingent upon the cellular milieu and the stage of oncogenesis ( Exercise has increasingly been recognized as a fundamental component of supportive oncology care, yielding significant advancements in the domains of fatigue reduction, cardiorespiratory fitness enhancement, muscle strength augmentation, and overall quality of life improvement ( In a concurrent manner, dietary polyphenolic compounds including resveratrol, curcumin, epigallocatechin gallate (EGCG), and quercetin, have exhibited properties that are anti-inflammatory, antioxidant, anti-fibrotic, and capable of modulating epigenetic mechanisms ( Crucially, the potential synergistic effects between structured physical exercise and polyphenol supplementation in addressing common molecular pathways have not been thoroughly synthesized within the framework of biomechanical dysfunction associated with cancer
