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The administration of an antioxidant food additive, butylated hydroxyanisole, mitigated the metastatic process (Chourasia et al

Disease simulation refers to how the disease is simulated in the study, including the realistic simulation of disease state (true): the animal model accurately replicates the pathological characteristics of the disease, including its clinical features, underlying mechanisms, and progression

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This is of particular importance for defining the redox secretome as opposed to the proteome, given the much lower concentration of secreted proteins compared to intracellular proteins