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OuJZhuXChenPDuYLuYPengXet alA randomized phase II trial of best supportive care with or without hyperthermia and vitamin C for heavily pretreated, advanced, refractory non-small-cell lung cancer

This stress-induced oxidative burden depletes glutathione reserves and may overwhelm cellular antioxidant defenses, potentially contributing to stress-related health consequences

Obesity in children is a risk factor for adult MetS (17)

Reduced cGMP signaling associated with neointimal proliferation and vascular dysfunction in late-stage atherosclerosis

Vitamin C - Antioxidant Power: Helps protect cells from oxidative damage

It is not yet FDA-approved, and momentum is building: in July 2026 an FDA advisory committee voted to recommend allowing licensed pharmacies to compound it, a recommendation now moving through the FDAs review