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Additionally, their antioxidant and anti-inflammatory properties may protect follicular cells from oxidative damage and immune-mediated disruption

But even high-purity peptide degrades if storage protocols fail

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10.1016/j.chembiol.2015.11.016 88 ShimadaK.SkoutaR.KaplanA.YangW

The compound did not advance to Phase 3 because the efficacy was insufficient for drug approval

Consequently, their safety profile and efficacy in Crohn's patients, particularly those with active inflammation or stricturing disease, has not been comprehensively established