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however, it has 3 major limitations: a low success rate in reducing intrabody aggregation, insufficient correlation between the estimated net negative charge of intrabodies at pH 7.4 with experimentally determined stability, and a lack of in vivo validation for the targeting of endogenous proteins 4

Dinchuk JE, Cao C, Huang F, Reeves KA, Wang J, Myers F, Cantor GH, Zhou X, Attar RM, Gottardis M, Carboni JM: Insulin receptor (IR) pathway hyperactivity in IGF-IR null cells and suppression of downstream growth signaling using the dual IGF-IR/IR inhibitor, BMS-754807

A 5-mC Dot Blot Assay Quantifying the DNA Methylation Level of Chondrocyte Dedifferentiation In Vitro

Maintenance of axonal function by local translation Whether mRNAs found in axon fractions are translated into axons or transported to the nucleus/cell body is an important question

In fact, we observed slightly enhanced neurite extension formation after adding tianma to the neuronal cells (Figure 2C)

FAD appears to be an inhibitory end-product that down-regulates its own formation