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Common symptoms include: Constant fatigue Weakness Pale skin Tingling or numbness Difficulty walking Memory problems Poor concentration Mood changes Mouth ulcers Breathlessness Loss of appetite Severe deficiency requires prompt medical evaluation

A month later, the couple used two super-sized cylinders before a flight to Mexico, and Oliveri's legs became so shaky that he had to hire an automated chair to get around the resort

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Direct insulin signaling of neurons reverses diabetic neuropathy

27 In general, patients with an irreversible cause should be treated indefinitely, whereas those with a reversible cause should be treated until the deficiency is corrected and symptoms resolve