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Modified Protocols for Elderly Patients Older adults might need different amounts of Vitamin B12

Some patients may require imaging studies (ultrasound, CT scanning) or referral to hepatology, haematology, or oncology services

Precautions General Precautions: Vitamin B 12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord

high levels of lactate dehydrogenase

Since Ruminiclostridium 6 was only observed in the LD control group, it was unsurprising that its relative abundance was significantly greater in this group compared to all other experimental groups (Supplementary Fig

First, nausea was the most commonly reported GI adverse event across all dose groups but showed a non-monotonic dose-response pattern, peaking at the 12 mg dose (35.9%) rather than the highest dose