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TGF 1 targets Smad, p38 MAPK, and PI 3K/Akt signaling pathways to induce PFKFB 3 gene expression and Glycolysis in glioblastoma cells

Understanding antibody epitope specificities and functional characteristics of cross-reactive antibodies following vaccination will further aid the development of antiviral countermeasures for SARS-CoV-2 and potential future CoV pandemic pathogens

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Mitochondrial Ca 2+ handling is also disrupted, leading to the opening of the mitochondrial permeability transition pore (mPTP) and the release of cytochrome c, which triggers apoptosis