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Table 2 Recommended daily intake for each B complex vitamin and the associated neurological and psychiatric manifestations resulting from their deficiencies

could modulate fibril formation and exacerbate -synuclein expression in the colon ( Akkermansia protein secretome, which dysregulates calcium homeostasis, leading to the promotion of calcium uptake in the mitochondria of entero-endocrine cells, triggering the formation of reactive oxygen species and subsequent -synuclein phosphorylation, aggregation, and deposition in vitro ( in vitro evaluation, it highlights previously unknown functions of distinct microbes in influencing the formation of pathogenic fibrils (Figure 2A)

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doi:10.1258/0022215001905120

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