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Thus, in this example, the initial indirect allocator would equal 6.00, resulting in a total PE RVU of 8.00 (2.00 is 25 percent of 8.00 and 6.00 is 75 percent of 8.00)

Together, these observations suggest that MEIS1-2 function to recruit KMT2D at lineage-specific, GATA-occupied enhancers to activate the cardiac gene expression program

Its involvement suggests that the hypomethylated state may favor transcriptional activation of metabolic pathways, potentially influencing systemic energy balance and inflammatory responses