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Biomarkers: Vitamin B12 is a vitamin which is necessary for the formation of red blood cells, tissue and cellular repairs and nerve health

Most research involves animal studies, and the Phase 1 human trial completed in 2015 never published results

And when I kind of spoke to my MD counterparts, I learned early on that this was more treating symptoms in the pharmaceutical approach rather than something that's treating kind of root cause medicine or underlying drivers

Serum cobalamin, homocysteine, and methylmalonic acid concentrations in a multiethnic elderly population: ethnic and sex differences in cobalamin and metabolite abnormalities

doi: 10.1186/S12864-024-10013-X 219 MillmanJRXieCVan DervortAGrtlerMPagliucaFWMeltonDA

It is helpful to maintain a regular sleep pattern, and may be useful to try warm baths before sleep