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In vitro and in vivo antioxidant potential of hydromethanolic extract of Phoenix dactylifera fruits

The authors were able to show increased damage to mitochondrial DNA in both idiopathic PD and in patients carrying the G2019S LRRK2 mutation, and found that mitochondrial DNA damage correlated with LRRK2 kinase activity

Recent studies have demonstrated the utility of supervised ML algorithms in predicting key disease outcomes including progression from simple steatosis to MASH, development of significant fibrosis, and even HCC

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The primary routes for permeation across the BBBinclude passive diffusion (lipid soluble solutes), ABC transporter efflux, carrier-mediated influx, and receptor-mediated transcytosis (Abbott et al., 2010)

These authors showed that the synbiotic based on Lactobacillus salivarius was involved in the activation of pathways related to fat and carbohydrate metabolism, cell adhesion, and immune response, while the synbiotic based on Lactobacillus plantarum was involved in the upregulation of expression of genes involved in metabolic pathways (154)