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Notably, NO and its derivatives (e.g., nitrite and nitrate) are more stable and less susceptible to rapid degradation under the antioxidant systems of serum 37 .The enzymatic antioxidants, including GPX, CAT, SOD and thioredoxin reductase (TrxR), play key roles in mitigating oxidative stress induced by ROS and free radicals 38

Take 1 capsule daily with a glass of water

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This particular feature has an important role in PD as several drugs have limited ability to cross the BBB on their own (123)

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.,JinY,TangX,CaoX,YuL,ChenJ,ZhaoHXuY4-((5-(Tert-butyl)-3-chloro-2-hydroxybenzyl) amino)-2-hydroxybenzoic acid protects against oxygen-glucose deprivation/reperfusion injury.2018;204:4654 102