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10.1073/pnas.1106750109 51 GohG

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Progression of cisplatin-induced nephrotoxicity in a carnitine-depleted rat model

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Biochemistry (Mosc.) 2000;65:856861

Abstract Purpose To elucidate mechanisms of renal excretion of pudexacianinium (ASP5354) and evaluate renal impairment effects on pharmacokinetics, safety, and tolerability of pudexacianinium

Comparing genomic AR binding patterns between benign prostate and localized primary CaP tissues, significant shifts were observed in malignant tissues where new malignant AR binding sites were found while benign AR sites were lost [57]