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108 Genetic interventions of PI3K demonstrated that cardiac-constitutively active PI3K (caPI3K) TG mice had larger hearts, while cardiac expression of a dnPI3K p110 mutant resulted in smaller hearts

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In particular, newly developed injectable hydrogels, which can be administered in situ, have been widely studied due to their advantages such as reducing systemic adverse reactions, drug dosage, and targeting of lesions [87]

423 The research further demonstrated that this anti-inflammatory effect was not mediated by GLP-1R in the blood or endothelial cells but required the GLP-1R in the CNS

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