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[241] [242] In contrast to human studies, adult female rats exhibit markedly greater dopamine release in the nucleus accumbens and more pronounced behavioral effects from amphetamine administration relative to males, effects that may be modulated by fluctuating estradiol levels across the estrous cycle or more broadly by adult gonadal hormones

Studies in which animals were exposed to various doses of marijuana for approximately 1230 months revealed immense damage to the smaller airways among dogs and monkeys

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