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Description

Molecular structure of the human CFTR ion channel

FNDC5/irisin knockout mice experience memory decline, whereas overexpression of FNDC5/irisin improves memory damage (Zhou et al., 2019)

10.1016/S1570-0232(03)00399-4 Summary Keywords acetaminophen, reactive metabolite, covalent binding, glutathione S -transferase, bottom-up proteomics, data-dependent acquisition, high-resolution tandem mass spectrometry, multiple reaction monitoring Citation Geib T, Lento C, Wilson DJ and Sleno L (2019) Liquid Chromatography-Tandem Mass Spectrometry Analysis of Acetaminophen Covalent Binding to Glutathione S -Transferases

We investigated plasma vanin-1 concentrations in 388 patients undergoing elective coronary angiography for suspected CAD

A minor portion of the drug is metabolized in the liver by the cytochrome P450 enzymes (primarily CYP2E1) to the reactive and toxic APAP intermediate, N -acetyl-p-benzoquinone imine (NAPQI) (Patten et al