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Furthermore, in a mouse model of CIRI, Propofol was shown to effectively prevent ferroptosis and protect against neuronal damage in the brain after cerebral ischemia/reperfusion

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10.1186/1471-2288-14-30 BMC Med Res Methodol

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Notably, NCOA4 is a selective autophagy receptor that is essential for mediating ferritin phagocytosis in certain tissues (for example, brain tissue) and cells (for example, red blood cells) (107,108)

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