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It converts uridine into pseudouridine in both mitochondria and cytosol, thus the clinical findings of both a mitochondrial myopathy and an autosomal recessive disorder

Sonnenberg, A., Janssen, H., Hogervorst, F., Calafat, J

In a depressive-like monkey model, significant changes in the gut microbiota were observed, and lipidomic analysis revealed abnormal lipid metabolism in brain regions (171)