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Ascorbate is another important cellular reductant inter-connected to the anti-oxidative response in chloroplast

3A), with no distinct clustering by sex (Suppl

These patients present with systemic sclerosis-like lesions, mild-to-moderate proximal muscle weakness, arthritis in the form of subluxation of the interphalangeal joints, mechanics hands, Raynaud phenomenon, and interstitial lung disease

Importantly, these residues, including His27, Lys59 and Tyr63 in LET7 TPR mediating polar interactions with HOP1, reside on the key interaction interface with LET7 PPase in the crystal structure of LET7/ At PAPP5 (PDB ID: 7OBE) 25 , further substantiating the idea that HOP1 displaces LET7 TPR from LET7 PPase to relieve the autoinhibition of LET7 catalytic activity

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