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Control of T reg and T H 17 cell differentiation by the aryl hydrocarbon receptor

10.1038/nature25460 189 MullarkyE.LuckiN

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The change in cysteine reactivity is measured using the isoTOP-ABPP approach, which is based on the labeling of reactive cysteines with isotopically tagged variants of the iodoacetamide-alkyne (IA-alkyne) probe ( via reductive isotope dimethyl labeling (ReDiMe) and quantitative mass spectrometry analysis ( E

[386], where OVA mice on a diet deficient in vitamin E had elevated levels of F2-isoprostanes

Thus, mutations in these critical areas are possible without completely disrupting the function of G6PD