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it appears to recapitulate the intracellular signals that exercise generates, including AMPK activation, mitochondrial biogenesis, and GLUT4 upregulation, in tissues that can no longer experience them through movement

Conover CA, Bale LK, Overgaard MT, Johnstone EW, Laursen UH, Fchtbauer EM, Oxvig C, van Deursen J

In controlled laboratory settings, this combination is widely utilised to examine connective tissue signalling, vascular response mechanisms, and coordinated recovery-related pathway activity