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As a central regulator of lipid metabolism, the PI3K/AKT pathway directly modulates key metabolic processes including fatty acid synthesis, catabolism, storage, lipid transport, and insulin sensitivity [37, 38]

In addition to those immune mediators that have been characterized, numerous other parasite-derived factors hypothesized to be involved in overcoming the immune response in the skin have been identified by genomic, transcriptomics and proteomic approaches ( Figure 2A )

Lowe, Senescence-induced vascular remodeling creates therapeutic vulnerabilities in pancreas cancer

Neuroimmunology Neuroinflammation

doi: 10.1016/j.cytogfr.2012.01.001 299 LiebKEngelbrechtMAGutOFiebichBLBauerJJanssenGet al

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