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Neuroprotective effects of Danshensu on rotenone-induced parkinsons disease models in vitro and in vivo

EomDWLeeJHKimYJHwangGSKimSNKwakJHet al

S., Pereira, K

Current pharmacological interventions for oxidative stress in the nervous systemsuch as edaravone (15, 16) and N-acetylcysteine (16, 17)act on single targets and employ relatively narrow mechanisms, and are associated with dose-limiting adverse effects and loss-of-benefit phenomena (e.g., end-of-dose deterioration and motor complications), rather than durable disease modification (18)

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