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Page MJ, Thomson GJA, Nunes JM, Engelbrecht AM, Nell TA, de Villiers WJS, et al

One study in ADHD that investigated markers of oxidative stress and inflammation showed that MPH downregulated c-FOS (gene involved in circadian rhythm) [148]

Alternative targets such as p-tau at threonine 217 (p-tau217) have been recently developed, showing better accuracy in Alzheimers 184 and may be more relevant to poor cognitive outcomes in PD