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*Correspondence: Wufei Zhu, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Therefore, the first amide bond between (2 S ,3 S )- t -ES and l-Ile is catalyzed by Cp1B, while formation of the second amide bond between 14 and putrescine is catalyzed by Cp1D (Fig

found that rapamycin (20 nM) combined with arsenic trioxide (0.5 and 1 M) has a synergistic antiproliferative and pro-apoptosis effect on AML cell lines (HL-60 and U-937) and primary AML cells that lack typical t (15;17) translocation

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