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Building upon mRNA structure optimization and delivery vector improvement, mRNA vaccines have demonstrated significant clinical efficacy during the COVID-19 pandemic, highlighting hallmark advantages of this platform including expedited manufacturing timelines, superior protective efficacy and eliminated genomic integration risks [20, 27]

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The aryl hydrocarbon receptor reduces LC3II expression and controls endoplasmic reticulum stress

We confirmed that lowering of Fas (activity) was beneficial to OLs since addition of Fas inhibitor C75 led to an increased differentiation in DA Wt but not in DA Gsta4 OLs

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