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Abstract Glutathione (GSH) is an endogenous tripeptide (Glu-Cys-Gly) and the most abundant endogenous antioxidant

For example, there is conflicting evidence for the formation of brunescence in the guinea pig lens (185, 186), unlike the characteristic time dependent increase in colouration observed in the human lens (187)

doi: 10.1038/s41591-019-0522-3 201 PaiJAHellmannMDSauterJLMattarMRizviHWooHJet al

In depression, while direct evidence linking NF-B and GPX4 remains limited, it has been established that both NF-B activation and GPX4 suppression contribute to brain injury, including neuronal loss, microglial overactivation, and reduced adult hippocampal neurogenesis (AHN) (Li et al., 2021

Jones, DC

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