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resistance is associated with lowered levels of glutathione

Participants consumed either a nitrate supplement or a placebo 2.5 h before testing in a randomized, crossover design

PMID: 17498508 DOI: 10.1053/j.gastro.2007.03.054 Boer GA et al (2023): Obesity pharmacotherapy: incretin action in the central nervous system

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2023) and proton magnetic resonance spectroscopy studies implicating glutamate abnormalities as well as increased levels of neuroinflammation in some patients (Filatova et al

Meta-analysis did not, however, note a significant effect size for GPx [38]