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This may be due to the complexation of copper to the small biologically active peptide, GHK 45

10.1038/nn.4476 38 FuscoW.BriccaL.KaitsasF.TartagliaM

Blinding was not used because the primary readouts in this study were based on objective measurements, including sequencing-based datasets, GPCR activity assays, metabolite quantification and flow cytometry, for which investigator awareness of group assignment was unlikely to influence data collection or analysis

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Of the patients with depression, 28 had moderate depression and 43 had severe depression at the time of the study

Gupta S, Aziz N, Sekhon L, Agarwal R, Mansour G, Li J, Agarwal A