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Much of the supporting data derives from animal models or correlative clinical observations, and therefore, this concept must be interpreted with caution (Rosca and Hoppel, 2010

In hypertensive mice induced by Ang II, TMAO changed the structure of Ang II by enhancing folding and processing of proteins, thereby prolonging the duration of hypertensive effect (119)

activation-and-transportation-of-fatty-acids-to-the-mitochondria-via-the-carnitine-shuttle 7 2017 "Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children"