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Clinical studies have shown that the chondrocytes in OA patients with articular cartilage injury greatly express MMP-13 (Salerno et al., 2020)

A 'respirator solution' contains the drug to be nebulized in concentrated form

[PMC free article] [PubMed] [Google Scholar] 86.Nguyen-Khac E., Thevenot T., Piquet M.A., Benferhat S., Goria O., Chatelain D., Tramier B., Dewaele F., Ghrib S., Rudler M., et al

The N-terminal glutamate of GSH formed a hydrogen bond with S85 of SjTGR at a distance of 2.2 , and the C-terminal glycine of GSH is stabilized by hydrogen bonds with K25 and Q60 of SjTGR at distances of 3.1 and 2.9 , respectively (Fig 3B)

Iskusnykh IY, Zakharova AA, Pathak D