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The search cutoff was August 2025, corresponding to the manuscript submission date, to ensure inclusion of the most up-to-date available evidence

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Although the ER controls the quality of newly generated proteins, pathological conditions such as renal disease, diabetes and atherosclerosis result in the accumulation of misfolded and unfolded proteins in the ER (2)

The surviving population of Teff cells remodels into memory T (Tm) cells which will later respond to future threats the Tm cells have previously experienced (11)

Hypersensitivity and cardiovascular risks related to allopurinol and febuxostat therapy in Asians: a population-based cohort study and meta-analysis

Townsend et al