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Novel piperonal 1,3,4-thiadiazolium-2-phenylamines mesoionic derivatives: synthesis, tyrosinase inhibition evaluation and HSA binding study

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This study aims to provide a comparative overview of the in vitro free radical scavenging potential and total metabolite contents of the mycelium and culture broth of 30 species from the IBK culture collection: Quantifying and comparing the total phenolic content (TPC) and total endo- (IPS) and exopolysaccharide (EPS) contents of the 30 species using advanced analytical techniques and assessing mycelium productivity

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Additionally, the strains are highly unstable, facing issues such as strain degeneration (e.g., abnormal color change, failure to form fruiting bodies) (Lou et al., 2019) during fruiting body cultivation and complex environmental responses during liquid fermentation