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Aromatics stocks were prepared in following concentrations: vanillate 200 mM, syringate, 3MGA, and gallate 100 mM

At Month 12, the mean change from baseline in ALP for patients with cirrhosis on seladelpar was -121.4 U/L vs 23.2 U/L for placebo, and -134.8 U/L for seladelpar vs -18.0 U/L for placebo in patients without cirrhosis

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However, such models are often more difficult to generate due to their less proliferative nature, and the heterogeneity of tumor microenvironments, cell(s)-of-origin, and genetic alterations