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Responses to immune-checkpoint inhibitors (ICIs) in patients with NSCLC correlate with a high TMB as well as with a high number of transversions as part of a smoking-related mutational signature 135

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That constant pairing can make them seem more established or clinically validated than they actually are, simply because theyre discussed together so often

[DOI] [PubMed] [Google Scholar] 6.McCracken J.T., McGough J., Shah B., Cronin P., Hong D., Aman M.G., Arnold L.E., Lindsay R., Nash P., Hollway J., et al