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218 LTB4 activates the BLT1 receptor on VSMC and induces VSMC activation and proliferation through an IKK-NF B-dependent pathway, which is important in early atherosclerotic formation

As reported, ROS generates hydrogen peroxide, which is a harmful molecule that can be scavenged by the glutathione peroxidase through GSH, it is found in the cytosol and the mitochondria, and by the catalase which is present in the peroxisomes