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it is available in liquid or tablet formulation and, based on clinical experience, it is used at doses up to 60 mg, t.i.d

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Glucocorticoids also promote the resolution of inflammation by inducing expression of scavenger receptors (e.g., CD153, CD206, and MERTK), anti-inflammatory cytokines (e.g., TGF- and IL-10), and the receptor for the pro-resolving lipid mediator, lipoxin A4, in human and murine macrophages, all of which potentiate macrophage phagocytosis and efferocytosis (97101)

GSH is synthesized in the cellular cytosol from its precursor amino acids Glu, Cys, and Gly, which are brought into the cell by specific transporters (Figure 2A) [12,13,14]

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Induction of autophagy in Cx3cr1+ mononuclear cells limits IL-23/IL-22 axis-mediated intestinal fibrosis