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However, semaglutide oral tablets are not approved for the reduction of CV events.As with other agents in this class, semaglutide has a boxed warning regarding rodent thyroid C-cell tumor findings and the uncertain relevance to humans.First-line T2DM therapy depends on comorbidities, patient-centered treatment factors, and management needs and generally includes metformin and comprehensive lifestyle modification

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Gastrointestinal side effects are the primary clinical concern: nausea (44%), diarrhea (30%), vomiting (24%), and constipation (24%) are common, particularly during dose escalation

[73] These are grown under special conditions to enhance yield