pancreatic cancer glutathione enhancement Increased glucose availability sensitizes to chemotherapy Glutathione prevents high glucose-induced pancreatic

Glutathione prevents high glucose induced pancreatic fibrosis by suppressing pancreatic stellate cell activation via the ROS TGF SMAD pathway Cell Death & Disease Emerging mechanisms and promising approaches in pancreatic cancer metabolism Cell Death & Disease Application of glutathione depletion in cancer therapy: Enhanced ROS based therapy, ferroptosis, and chemotherapy ScienceDirect Beyond the tumor: Enhancing pancreatic cancer therapy through glutamine metabolism and innovative drug delivery Su 2025 Journal of Cell Communication and Signaling Wiley Online Library Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4 dependent ferroptosis: Cell Reports Medicine Glutathione metabolism is essential for self renewal and chemoresistance of pancreatic cancer stem cells PMC

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